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MURC deficiency in smooth muscle attenuates pulmonary hypertension

Emerging evidence suggests that caveolin-1 (Cav1) is associated with pulmonary arterial hypertension. MURC (also called Cavin-4) is a member of the cavin family, which regulates caveolar formation and functions together with caveolins. Here, we show that hypoxia increased Murc mRNA expression in the...

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Detalles Bibliográficos
Autores principales: Nakanishi, Naohiko, Ogata, Takehiro, Naito, Daisuke, Miyagawa, Kotaro, Taniguchi, Takuya, Hamaoka, Tetsuro, Maruyama, Naoki, Kasahara, Takeru, Nishi, Masahiro, Matoba, Satoaki, Ueyama, Tomomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996946/
https://www.ncbi.nlm.nih.gov/pubmed/27546070
http://dx.doi.org/10.1038/ncomms12417