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Topology and structure of an engineered human cohesin complex bound to Pds5B

The cohesin subunits Smc1, Smc3 and Scc1 form large tripartite rings which mediate sister chromatid cohesion and chromatin structure. These are thought to entrap DNA with the help of the associated proteins SA1/2 and Pds5A/B. Structural information is available for parts of cohesin, but analyses of...

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Detalles Bibliográficos
Autores principales: Hons, Michael T., Huis in ‘t Veld, Pim J., Kaesler, Jan, Rombaut, Pascaline, Schleiffer, Alexander, Herzog, Franz, Stark, Holger, Peters, Jan-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996973/
https://www.ncbi.nlm.nih.gov/pubmed/27549742
http://dx.doi.org/10.1038/ncomms12523