Sequence-Based Screening for Rare Enzymes: New Insights into the World of AMDases Reveal a Conserved Motif and 58 Novel Enzymes Clustering in Eight Distinct Families

Arylmalonate Decarboxylases (AMDases, EC 4.1.1.76) are very rare and mostly underexplored enzymes. Currently only four known and biochemically characterized representatives exist. However, their ability to decarboxylate α-disubstituted malonic acid derivatives to optically pure products without cofa...

Descripción completa

Detalles Bibliográficos
Autores principales: Maimanakos, Janine, Chow, Jennifer, Gaßmeyer, Sarah K., Güllert, Simon, Busch, Florian, Kourist, Robert, Streit, Wolfgang R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996985/
https://www.ncbi.nlm.nih.gov/pubmed/27610105
http://dx.doi.org/10.3389/fmicb.2016.01332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996985/
https://www.ncbi.nlm.nih.gov/pubmed/27610105
http://dx.doi.org/10.3389/fmicb.2016.01332

Ejemplares similares