The Overexpression of TDP-43 Protein in the Neuron and Oligodendrocyte Cells Causes the Progressive Motor Neuron Degeneration in the SOD1 G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

The recent investigation suggested that the TDP-43 protein was closely related to the motor neuron degeneration in amyotrophic lateral sclerosis (ALS), but the pathogenesis contributed to motor neuron degeneration largely remained unknown. Therefore, we detected the alteration of TDP-43 expression a...

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Detalles Bibliográficos
Autores principales: Lu, Yi, Tang, Chunyan, Zhu, Lei, Li, Jiao, Liang, Huiting, Zhang, Jie, Xu, Renshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997058/
https://www.ncbi.nlm.nih.gov/pubmed/27570488
http://dx.doi.org/10.7150/ijbs.15938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997058/
https://www.ncbi.nlm.nih.gov/pubmed/27570488
http://dx.doi.org/10.7150/ijbs.15938

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