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CD146-targeted immunoPET and NIRF Imaging of Hepatocellular Carcinoma with a Dual-Labeled Monoclonal Antibody

Overexpression of CD146 has been correlated with aggressiveness, recurrence rate, and poor overall survival in hepatocellular carcinoma (HCC) patients. In this study, we set out to develop a CD146-targeting probe for high-contrast noninvasive in vivo positron emission tomography (PET) and near-infra...

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Detalles Bibliográficos
Autores principales: Hernandez, Reinier, Sun, Haiyan, England, Christopher G., Valdovinos, Hector F., Ehlerding, Emily B., Barnhart, Todd E., Yang, Yunan, Cai, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997246/
https://www.ncbi.nlm.nih.gov/pubmed/27570560
http://dx.doi.org/10.7150/thno.15568