Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages

Tumor necrosis factor (TNF) is best known for inducing a rapid but transient NF-κB-mediated inflammatory response. We investigated later phases of TNF signaling, after the initial transient induction of inflammatory genes has subsided, in primary human macrophages. TNF signaling induced expression o...

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Detalles Bibliográficos
Autores principales: Huynh, Linda, Kusnadi, Anthony, Park, Sung Ho, Murata, Koichi, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997257/
https://www.ncbi.nlm.nih.gov/pubmed/27558590
http://dx.doi.org/10.1038/srep31959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997257/
https://www.ncbi.nlm.nih.gov/pubmed/27558590
http://dx.doi.org/10.1038/srep31959

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