Cargando…
Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages
Tumor necrosis factor (TNF) is best known for inducing a rapid but transient NF-κB-mediated inflammatory response. We investigated later phases of TNF signaling, after the initial transient induction of inflammatory genes has subsided, in primary human macrophages. TNF signaling induced expression o...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997257/ https://www.ncbi.nlm.nih.gov/pubmed/27558590 http://dx.doi.org/10.1038/srep31959 |