HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer’s disease

Alzheimer’s disease (AD) is the most common neurodegenerative disease, but it remains an intractable condition. Its pathogenesis is predominantly attributed to the aggregation and transmission of two molecules, Aβ and tau; however, other pathological mechanisms are possible. Here, we reveal that pho...

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Detalles Bibliográficos
Autores principales: Fujita, Kyota, Motoki, Kazumi, Tagawa, Kazuhiko, Chen, Xigui, Hama, Hiroshi, Nakajima, Kazuyuki, Homma, Hidenori, Tamura, Takuya, Watanabe, Hirohisa, Katsuno, Masahisa, Matsumi, Chiemi, Kajikawa, Masunori, Saito, Takashi, Saido, Takaomi, Sobue, Gen, Miyawaki, Atsushi, Okazawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997258/
https://www.ncbi.nlm.nih.gov/pubmed/27557632
http://dx.doi.org/10.1038/srep31895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997258/
https://www.ncbi.nlm.nih.gov/pubmed/27557632
http://dx.doi.org/10.1038/srep31895

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