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Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways

There is an integral relationship between vascular cells and leukocytes in supporting healthy tissue homeostasis. Furthermore, activation of these two cellular components is key for tissue repair following injury. Toll-like receptors (TLRs) play a role in innate immunity defending the organism again...

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Detalles Bibliográficos
Autores principales: Wu, Jiahui, Su, Wenru, Powner, Michael B., Liu, Jian, Copland, David A., Fruttiger, Marcus, Madeddu, Paolo, Dick, Andrew D., Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997267/
https://www.ncbi.nlm.nih.gov/pubmed/27558877
http://dx.doi.org/10.1038/srep31873