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The emergence of superstructural order in insulin amyloid fibrils upon multiple rounds of self-seeding
Typically, elongation of an amyloid fibril entails passing conformational details of the mother seed to daughter generations of fibrils with high fidelity. There are, however, several factors that can potentially prevent such transgenerational structural imprinting from perpetuating, for example het...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997315/ https://www.ncbi.nlm.nih.gov/pubmed/27558445 http://dx.doi.org/10.1038/srep32022 |