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Detection of nucleotide-specific CRISPR/Cas9 modified alleles using multiplex ligation detection
CRISPR/Cas9 genome-editing has emerged as a powerful tool to create mutant alleles in model organisms. However, the precision with which these mutations are created has introduced a new set of complications for genotyping and colony management. Traditional gene-targeting approaches in many experimen...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997339/ https://www.ncbi.nlm.nih.gov/pubmed/27557703 http://dx.doi.org/10.1038/srep32048 |