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Correlation of CpG Island Methylation of the Cytochrome P450 2E1/2D6 Genes with Liver Injury Induced by Anti-Tuberculosis Drugs: A Nested Case-Control Study

This study investigated the role of CpG island methylation of the CYP2E1 and CYP2D6 genes in liver injury induced by anti-TB drugs from an epigenetic perspective in a Chinese cohort. A 1:1 matched nested case-control study design was applied. Pulmonary tuberculosis (TB) patients, who underwent stand...

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Detalles Bibliográficos
Autores principales: Zhang, Jinling, Zhu, Xuebin, Li, Yuhong, Zhu, Lingyan, Li, Shiming, Zheng, Guoying, Ren, Qi, Xiao, Yonghong, Feng, Fumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997462/
https://www.ncbi.nlm.nih.gov/pubmed/27490558
http://dx.doi.org/10.3390/ijerph13080776