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Wedelolactone enhances osteoblastogenesis by regulating Wnt/β-catenin signaling pathway but suppresses osteoclastogenesis by NF-κB/c-fos/NFATc1 pathway

Bone homeostasis is maintained by formation and destruction of bone, which are two processes tightly coupled and controlled. Targeting both stimulation on bone formation and suppression on bone resorption becomes a promising strategy for treating osteoporosis. In this study, we examined the effect o...

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Detalles Bibliográficos
Autores principales: Liu, Yan-Qiu, Hong, Zhi-Lai, Zhan, Li-Bin, Chu, Hui-Ying, Zhang, Xiao-Zhe, Li, Guo-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997609/
https://www.ncbi.nlm.nih.gov/pubmed/27558652
http://dx.doi.org/10.1038/srep32260