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Wedelolactone enhances osteoblastogenesis by regulating Wnt/β-catenin signaling pathway but suppresses osteoclastogenesis by NF-κB/c-fos/NFATc1 pathway
Bone homeostasis is maintained by formation and destruction of bone, which are two processes tightly coupled and controlled. Targeting both stimulation on bone formation and suppression on bone resorption becomes a promising strategy for treating osteoporosis. In this study, we examined the effect o...
Autores principales: | Liu, Yan-Qiu, Hong, Zhi-Lai, Zhan, Li-Bin, Chu, Hui-Ying, Zhang, Xiao-Zhe, Li, Guo-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997609/ https://www.ncbi.nlm.nih.gov/pubmed/27558652 http://dx.doi.org/10.1038/srep32260 |
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