Mechanism and role of MCP-1 upregulation upon chikungunya virus infection in human peripheral blood mononuclear cells

Monocyte chemoattractant protein-1 (MCP-1/CCL2)-mediated migration of monocytes is essential for immunological surveillance of tissues. During chikungunya virus (CHIKV) infection however, excessive production of MCP-1 has been linked to disease pathogenesis. High MCP-1 serum levels are detected duri...

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Detalles Bibliográficos
Autores principales: Ruiz Silva, Mariana, van der Ende-Metselaar, Heidi, Mulder, H. Lie, Smit, Jolanda M., Rodenhuis-Zybert, Izabela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997611/
https://www.ncbi.nlm.nih.gov/pubmed/27558873
http://dx.doi.org/10.1038/srep32288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997611/
https://www.ncbi.nlm.nih.gov/pubmed/27558873
http://dx.doi.org/10.1038/srep32288

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