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Efficacy and safety of bevacizumab plus chemotherapy compared to chemotherapy alone in previously untreated advanced or metastatic colorectal cancer: a systematic review and meta-analysis

BACKGROUND: Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second leading cause of neoplasm-related death in the United States. Several studies analyzed the efficacy of bevacizumab combined with different chemotherapy regimens consisting on drugs such as 5-FU, capecit...

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Detalles Bibliográficos
Autores principales: Botrel, Tobias Engel Ayer, Clark, Luciana Gontijo de Oliveira, Paladini, Luciano, Clark, Otávio Augusto C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997727/
https://www.ncbi.nlm.nih.gov/pubmed/27558497
http://dx.doi.org/10.1186/s12885-016-2734-y