Acidification changes affect the inflammasome in human nucleus pulposus cells

BACKGROUND: Interleukin (IL)-1β is involved in the pathology of intervertebral disc degeneration. Under normal conditions, IL-1β is present in cells in an inactive form (pro-IL-1β). However, under pathological conditions, pro-IL-1β is turned into its active form (IL-1β) by the inflammasome, a multi-...

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Detalles Bibliográficos
Autores principales: Brand, Frank J., Forouzandeh, Mahtab, Kaur, Harmanpreet, Travascio, Francesco, de Rivero Vaccari, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997758/
https://www.ncbi.nlm.nih.gov/pubmed/27563282
http://dx.doi.org/10.1186/s12950-016-0137-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997758/
https://www.ncbi.nlm.nih.gov/pubmed/27563282
http://dx.doi.org/10.1186/s12950-016-0137-0

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