The multi-omic landscape of transcription factor inactivation in cancer

BACKGROUND: Hypermethylation of transcription factor promoters bivalently marked in stem cells is a cancer hallmark. However, the biological significance of this observation for carcinogenesis is unclear given that most of these transcription factors are not expressed in any given normal tissue. MET...

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Detalles Bibliográficos
Autores principales: Teschendorff, Andrew E., Zheng, Shijie C., Feber, Andy, Yang, Zhen, Beck, Stephan, Widschwendter, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997779/
https://www.ncbi.nlm.nih.gov/pubmed/27562343
http://dx.doi.org/10.1186/s13073-016-0342-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997779/
https://www.ncbi.nlm.nih.gov/pubmed/27562343
http://dx.doi.org/10.1186/s13073-016-0342-8

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