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Overexpression of TAZ promotes cell proliferation, migration and epithelial-mesenchymal transition in ovarian cancer

The Hippo pathway is dysregulated in multiple types of human cancer, including ovarian cancer. Nuclear expression of yes-associated protein 1 (YAP1), a downstream transcription coactivator of the Hippo pathway, has been demonstrated to promote tumorigenesis in ovarian cancer and may serve as a poor...

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Detalles Bibliográficos
Autores principales: Chen, Guangyuan, Xie, Jiabin, Huang, Ping, Yang, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997911/
https://www.ncbi.nlm.nih.gov/pubmed/27588129
http://dx.doi.org/10.3892/ol.2016.4829