Platycodin D Induces Tumor Growth Arrest by Activating FOXO3a Expression in Prostate Cancer in vitro and in vivo

Platycodin D (PD), a major saponin derived from Platycodin grandiflorum, exerted cytotoxicity against prostate cancer cell lines (PC3, DU145 and LNCaP cells) with IC(50) values in the range of 11.17 to 26.13μmol/L, whereas RWPE-1cells (a non-malignant human prostate epithelial cell line) were not si...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Rui, Lu, Zongliang, Liu, Kai, Guo, Jing, Liu, Jie, Zhou, Yong, Yang, Jian, Mi, Mantian, Xu, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997962/
https://www.ncbi.nlm.nih.gov/pubmed/25431082
http://dx.doi.org/10.2174/1568009614666141128104642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997962/
https://www.ncbi.nlm.nih.gov/pubmed/25431082
http://dx.doi.org/10.2174/1568009614666141128104642

Ejemplares similares