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Platycodin D Induces Tumor Growth Arrest by Activating FOXO3a Expression in Prostate Cancer in vitro and in vivo

Platycodin D (PD), a major saponin derived from Platycodin grandiflorum, exerted cytotoxicity against prostate cancer cell lines (PC3, DU145 and LNCaP cells) with IC(50) values in the range of 11.17 to 26.13μmol/L, whereas RWPE-1cells (a non-malignant human prostate epithelial cell line) were not si...

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Detalles Bibliográficos
Autores principales:	Zhou, Rui, Lu, Zongliang, Liu, Kai, Guo, Jing, Liu, Jie, Zhou, Yong, Yang, Jian, Mi, Mantian, Xu, Hongxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997962/ https://www.ncbi.nlm.nih.gov/pubmed/25431082 http://dx.doi.org/10.2174/1568009614666141128104642

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