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Glutamine decreases intestinal mucosal injury in a rat model of intestinal ischemia-reperfusion by downregulating HMGB1 and inflammatory cytokine expression

Intestinal ischemia-reperfusion (IR) is a common clinical pathophysiological process that is common in severe trauma, major surgery, and in post-resuscitation. Glutamine (Gln) reduces intestinal IR injury, however, its mechanism of action remains to be determined. High mobility group box 1 (HMGB1) p...

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Detalles Bibliográficos
Autores principales: Shu, Xiaoliang, Zhang, Jian, Wang, Qingxiu, Xu, Zengguang, Yu, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998012/
https://www.ncbi.nlm.nih.gov/pubmed/27588057
http://dx.doi.org/10.3892/etm.2016.3468