Combination of hydrotropic nicotinamide with nanoparticles for enhancing tacrolimus percutaneous delivery

Tacrolimus (FK506), an effective immunosuppressant for treating inflammatory skin diseases, hardly penetrates into and through the skin owing to its high hydrophobicity and molecular weight. The aim of this study was to develop a hybrid system based on nicotinamide (NIC) and nanoparticles (NPs) enca...

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Detalles Bibliográficos
Autores principales: Pan, Wenhui, Qin, Mengyao, Zhang, Guoguang, Long, Yueming, Ruan, Wenyi, Pan, Jingtong, Wu, Zushuai, Wan, Tao, Wu, Chuanbin, Xu, Yuehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998035/
https://www.ncbi.nlm.nih.gov/pubmed/27578973
http://dx.doi.org/10.2147/IJN.S108545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998035/
https://www.ncbi.nlm.nih.gov/pubmed/27578973
http://dx.doi.org/10.2147/IJN.S108545

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