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Valproic acid induces autophagy by suppressing the Akt/mTOR pathway in human prostate cancer cells

Previous studies have demonstrated that the chronic administration of valproic acid (VPA) suppresses angiogenesis in vivo; however, the mechanisms implicated in VPA-induced autophagy remain unclear. The current study aimed to assess VPA-induced autophagy in three prostate cancer cell lines (PC3, DU1...

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Detalles Bibliográficos
Autores principales: Xia, Qinghua, Zheng, Yi, Jiang, Wei, Huang, Zhongxian, Wang, Muwen, Rodriguez, Ronald, Jin, Xunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998110/
https://www.ncbi.nlm.nih.gov/pubmed/27588130
http://dx.doi.org/10.3892/ol.2016.4880