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Anti-4-1BB monoclonal antibodies attenuate concanavalin A-induced immune-mediated liver injury in mice
Effective therapies for the treatment of immune-mediated liver disease are currently lacking. As a member of the tumor necrosis factor receptor superfamily, 4-1BB has a key role in T-cell activation and has been implicated in the development of autoimmune disorders. The purpose of the present study...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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D.A. Spandidos
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998111/ https://www.ncbi.nlm.nih.gov/pubmed/27588047 http://dx.doi.org/10.3892/etm.2016.3503 |