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4-HPR impairs bladder cancer cell migration and invasion by interfering with the Wnt5a/JNK and Wnt5a/MMP-2 signaling pathways

In order to identify the anti-invasive and anti-metastatic effect of the synthetic retinoid N-(4-hydroxyphenyl) retinamide (4-HPR) on the human bladder cancer EJ cell line, and to study its impact on the expression of wingless-type mouse mammary tumor virus integration site family, member 5a (Wnt5a)...

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Detalles Bibliográficos
Autores principales: Cao, Yuanfei, Wang, Xiaolong, Xu, Chang, Gao, Zhengyan, Zhou, Haihong, Wang, Yongzhi, Cao, Rui, Liu, Tao, Liu, Tongzu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998198/
https://www.ncbi.nlm.nih.gov/pubmed/27602114
http://dx.doi.org/10.3892/ol.2016.4908