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Augmented expression of Polo-like kinase 1 is a strong predictor of shorter cancer-specific overall survival in early stage breast cancer at 15-year follow-up

Polo-like kinase 1 (PLK1) is a serine-threonine kinase that plays a crucial role in the regulation of cell division. In addition, it acts as a modulator of the DNA damage response and as a novel factor in the maintenance of genome stability during DNA replication. The present study aimed to reveal t...

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Detalles Bibliográficos
Autores principales: Donizy, Piotr, Halon, Agnieszka, Surowiak, Pawel, Kaczorowski, Maciej, Kozyra, Cyprian, Matkowski, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998224/
https://www.ncbi.nlm.nih.gov/pubmed/27602103
http://dx.doi.org/10.3892/ol.2016.4890