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Alternative splicing of spleen tyrosine kinase differentially regulates colorectal cancer progression

Spleen tyrosine kinase (SYK) has been reported as a potential tumor suppressor in colorectal cancer (CRC). However, the role of alternative splicing of SYK in carcinogenesis remains unclear. In the present study, SYK isoforms were overexpressed in the human CRC HCT 116 cell line using lentiviral exp...

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Detalles Bibliográficos
Autores principales: Ni, Beibei, Hu, Jun, Chen, Dianke, Li, Li, Chen, Daici, Wang, Jianping, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998349/
https://www.ncbi.nlm.nih.gov/pubmed/27602108
http://dx.doi.org/10.3892/ol.2016.4858