Recombinant thrombomodulin for secondary thrombotic thrombocytopenic purpura

In the pathogenesis of thrombotic thrombocytopenic purpura (TTP), reductions in the enzyme activity of ADAMTS13, which cuts ultralarge von Willebrand multimers, generates shear stress on the microvascular endothelium, leading to platelet aggregation and the formation of a thrombus. ADAMTS13 activity...

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Detalles Bibliográficos
Autores principales: Nakamura, Kensuke, Inokuchi, Ryota, Hiruma, Takahiro, Ohshima, Kazuma, Sonoo, Tomohiro, Tokunaga, Kurato, Doi, Kent, Nakajima, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
3900
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998437/
https://www.ncbi.nlm.nih.gov/pubmed/27310951
http://dx.doi.org/10.1097/MD.0000000000003712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998437/
https://www.ncbi.nlm.nih.gov/pubmed/27310951
http://dx.doi.org/10.1097/MD.0000000000003712

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