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Trimethoprim/Sulfamethoxazole-Induced Severe Lactic Acidosis: A Case Report and Review of the Literature

Propylene glycol (PG) is used as a solvent in numerous medications, including trimethoprim/sulfamethoxazole (TMP/SMX) and lorazepam, and is metabolized in the liver to lactic acid. Cases of lactic acidosis related to PG toxicity have been described and always involved large doses of benzodiazepines...

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Detalles Bibliográficos
Autores principales: Bulathsinghala, Marie, Keefer, Kimberly, Van de Louw, Andry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998708/
https://www.ncbi.nlm.nih.gov/pubmed/27124045
http://dx.doi.org/10.1097/MD.0000000000003478