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High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire
The T-cell receptor (TCR) repertoire is a mirror of the human immune system that reflects processes caused by infections, cancer, autoimmunity, and aging. Next-generation sequencing has become a powerful tool for deep TCR profiling. Herein, we used this technology to study the repertoire features of...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998859/ https://www.ncbi.nlm.nih.gov/pubmed/26962778 http://dx.doi.org/10.1097/MD.0000000000002839 |