Autocrine VEGFR1 and VEGFR2 signaling promotes survival in human glioblastoma models in vitro and in vivo

BACKGROUND: Although the vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) system has become a prime target for antiangiogenic treatment, its biological role in glioblastoma beyond angiogenesis has remained controversial. METHODS: Using neutralizing antibodies to VEGF or placental grow...

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Detalles Bibliográficos
Autores principales: Szabo, Emese, Schneider, Hannah, Seystahl, Katharina, Rushing, Elisabeth Jane, Herting, Frank, Weidner, K. Michael, Weller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Basic and Translational Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998998/
https://www.ncbi.nlm.nih.gov/pubmed/27009237
http://dx.doi.org/10.1093/neuonc/now043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998998/
https://www.ncbi.nlm.nih.gov/pubmed/27009237
http://dx.doi.org/10.1093/neuonc/now043

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