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A scale‐down mimic for mapping the process performance of centrifugation, depth and sterile filtration

In the production of biopharmaceuticals disk‐stack centrifugation is widely used as a harvest step for the removal of cells and cellular debris. Depth filters followed by sterile filters are often then employed to remove residual solids remaining in the centrate. Process development of centrifugatio...

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Detalles Bibliográficos
Autores principales: Joseph, Adrian, Kenty, Brian, Mollet, Michael, Hwang, Kenneth, Rose, Steven, Goldrick, Stephen, Bender, Jean, Farid, Suzanne S., Titchener‐Hooker, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999036/
https://www.ncbi.nlm.nih.gov/pubmed/26927621
http://dx.doi.org/10.1002/bit.25967