Synthetic strategy and antiviral evaluation of diamide containing heterocycles targeting dengue and yellow fever virus()

High-throughput screening of a subset of the CD3 chemical library (Centre for Drug Design and Discovery; KU Leuven) provided us with a lead compound 1, displaying low micromolar potency against dengue virus and yellow fever virus. Within a project aimed at discovering new inhibitors of flaviviruses,...

Descripción completa

Detalles Bibliográficos
Autores principales: Saudi, Milind, Zmurko, Joanna, Kaptein, Suzanne, Rozenski, Jef, Gadakh, Bharat, Chaltin, Patrick, Marchand, Arnaud, Neyts, Johan, Van Aerschot, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editions Scientifiques Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999056/
https://www.ncbi.nlm.nih.gov/pubmed/27240271
http://dx.doi.org/10.1016/j.ejmech.2016.05.043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999056/
https://www.ncbi.nlm.nih.gov/pubmed/27240271
http://dx.doi.org/10.1016/j.ejmech.2016.05.043

Ejemplares similares