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Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro

Microtubule structure and functions have been widely studied in vitro and in cells. Research has shown that cysteines on tubulin play a crucial role in the polymerization of microtubules. Here, we show that blocking sulfhydryl groups of cysteines in taxol-stabilized polymerized microtubules with a c...

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Detalles Bibliográficos
Autores principales: Prabhune, Meenakshi, von Roden, Kerstin, Rehfeldt, Florian, Schmidt, Christoph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999061/
https://www.ncbi.nlm.nih.gov/pubmed/27561096
http://dx.doi.org/10.1371/journal.pone.0161623