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The Effect of Vector Silencing during Picornavirus Vaccination against Experimental Melanoma and Glioma

Virus vector-based vaccination against tumor-specific antigens remains a promising therapeutic approach to overcome the immune suppressive tumor microenvironment. However, the extent that the desired CD8 T cell response against the targeted tumor antigen is impacted by the CD8 T cell response agains...

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Detalles Bibliográficos
Autores principales: Malo, Courtney S., Renner, Danielle N., Huseby Kelcher, April M., Jin, Fang, Hansen, Michael J., Pavelko, Kevin D., Johnson, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999064/
https://www.ncbi.nlm.nih.gov/pubmed/27560502
http://dx.doi.org/10.1371/journal.pone.0162064