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The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity

Defensins are frontline peptides of mucosal immunity in the animal kingdom, including birds. Their resistance to proteolysis and their ensuing ability to maintain antimicrobial potential remains questionable and was therefore investigated. We have shown by bottom-up mass spectrometry analysis of pro...

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Detalles Bibliográficos
Autores principales: Bailleul, Geoffrey, Kravtzoff, Amanda, Joulin-Giet, Alix, Lecaille, Fabien, Labas, Valérie, Meudal, Hervé, Loth, Karine, Teixeira-Gomes, Ana-Paula, Gilbert, Florence B., Coquet, Laurent, Jouenne, Thierry, Brömme, Dieter, Schouler, Catherine, Landon, Céline, Lalmanach, Gilles, Lalmanach, Anne-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999073/
https://www.ncbi.nlm.nih.gov/pubmed/27561012
http://dx.doi.org/10.1371/journal.pone.0161573