A Novel SCN5A Mutation Associated with Drug Induced Brugada Type ECG

BACKGROUND: Class IC antiarrhythmic agents may induce acquired forms of Brugada Syndrome. We have identified a novel mutation in SCN5A, the gene that encodes the α-subunit of the human cardiac sodium channel (hNa(v)1.5), in a patient who exhibited Brugada- type ECG changes during pharmacotherapy of...

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Detalles Bibliográficos
Autores principales: Turker, Isik, Makiyama, Takeru, Vatta, Matteo, Itoh, Hideki, Ueyama, Takeshi, Shimizu, Akihiko, Ai, Tomohiko, Horie, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999187/
https://www.ncbi.nlm.nih.gov/pubmed/27560382
http://dx.doi.org/10.1371/journal.pone.0161872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999187/
https://www.ncbi.nlm.nih.gov/pubmed/27560382
http://dx.doi.org/10.1371/journal.pone.0161872

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