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Regulation of Polycystin-1 Function by Calmodulin Binding

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a common genetic disease that leads to progressive renal cyst growth and loss of renal function, and is caused by mutations in the genes encoding polycystin-1 (PC1) and polycystin-2 (PC2), respectively. The PC1/PC2 complex localizes to primary...

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Detalles Bibliográficos
Autores principales: Doerr, Nicholas, Wang, Yidi, Kipp, Kevin R., Liu, Guangyi, Benza, Jesse J., Pletnev, Vladimir, Pavlov, Tengis S., Staruschenko, Alexander, Mohieldin, Ashraf M., Takahashi, Maki, Nauli, Surya M., Weimbs, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999191/
https://www.ncbi.nlm.nih.gov/pubmed/27560828
http://dx.doi.org/10.1371/journal.pone.0161525