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HIV-Infected Children Have Lower Frequencies of CD8+ Mucosal-Associated Invariant T (MAIT) Cells that Correlate with Innate, Th17 and Th22 Cell Subsets

Mucosal-associated invariant T cells (MAIT) are innate T cells restricted by major histocompatibility related molecule 1 (MR1) presenting riboflavin metabolite ligands derived from microbes. Specificity to riboflavin metabolites confers MAIT cells a broad array of host-protective activity against gr...

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Detalles Bibliográficos
Autores principales: Khaitan, Alka, Kilberg, Max, Kravietz, Adam, Ilmet, Tiina, Tastan, Cihan, Mwamzuka, Mussa, Marshed, Fatma, Liu, Mengling, Ahmed, Aabid, Borkowsky, William, Unutmaz, Derya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999196/
https://www.ncbi.nlm.nih.gov/pubmed/27560150
http://dx.doi.org/10.1371/journal.pone.0161786