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SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells

SWAP-70 and DEF6, two proteins that feature similar domain and motif arrangements, are mainly known for their functions in differentiated hematopoietic cells. Both proteins interact with and regulate RhoGTPases and F-actin dynamics, yet their role in hematopoietic stem and precursor cells (HSPCs) re...

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Detalles Bibliográficos
Autores principales: Ripich, Tatsiana, Chacón-Martínez, Carlos Andrés, Fischer, Luise, Pernis, Alessandra, Kiessling, Nadine, Garbe, Annette I., Jessberger, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999197/
https://www.ncbi.nlm.nih.gov/pubmed/27561029
http://dx.doi.org/10.1371/journal.pone.0161060