Amlexanox Blocks the Interaction between S100A4 and Epidermal Growth Factor and Inhibits Cell Proliferation

The human S100A4 protein binds calcium, resulting in a change in its conformation to promote the interaction with its target protein. Human epidermal growth factor (EGF) is the target protein of S100A4 and a critical ligand of the receptor EGFR. The EGF/EGFR system promotes cell survival, differenti...

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Detalles Bibliográficos
Autores principales: Cho, Ching Chang, Chou, Ruey-Hwang, Yu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999211/
https://www.ncbi.nlm.nih.gov/pubmed/27559743
http://dx.doi.org/10.1371/journal.pone.0161663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999211/
https://www.ncbi.nlm.nih.gov/pubmed/27559743
http://dx.doi.org/10.1371/journal.pone.0161663

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