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FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children?

BACKGROUND: Genome-wide association studies have identified variants within the FTO (fat mass and obesity associated) locus as the strongest predictors of obesity amongst all obesity-associated gene loci. Recent evidence suggests that variants in FTO directly affect human adipocyte function through...

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Detalles Bibliográficos
Autores principales: Landgraf, Kathrin, Scholz, Markus, Kovacs, Peter, Kiess, Wieland, Körner, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999231/
https://www.ncbi.nlm.nih.gov/pubmed/27560134
http://dx.doi.org/10.1371/journal.pone.0161739