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Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury
Myocardial infarction results in compromised myocardial function with heart failure due to insufficient cardiomyocyte self-renewal(1). Unlike lower vertebrates, mammalian hearts only have a transient neonatal renewal capacity(2). Reactivating primitive reparative ability in the mature heart requires...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999251/ https://www.ncbi.nlm.nih.gov/pubmed/27251288 http://dx.doi.org/10.1038/nature17959 |