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Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury

Myocardial infarction results in compromised myocardial function with heart failure due to insufficient cardiomyocyte self-renewal(1). Unlike lower vertebrates, mammalian hearts only have a transient neonatal renewal capacity(2). Reactivating primitive reparative ability in the mature heart requires...

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Detalles Bibliográficos
Autores principales: Tao, Ge, Kahr, Peter C., Morikawa, Yuka, Zhang, Min, Rahmani, Mahdis, Heallen, Todd R., Li, Lele, Sun, Zhao, Olson, Eric N., Amendt, Brad A., Martin, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999251/
https://www.ncbi.nlm.nih.gov/pubmed/27251288
http://dx.doi.org/10.1038/nature17959