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A Comprehensive Analysis of Plasmodium Circumsporozoite Protein Binding to Hepatocytes

Circumsporozoite protein (CSP) is the dominant protein on the surface of Plasmodium sporozoites and plays a critical role in the invasion by sporozoites of hepatocytes. Contacts between CSP and heparin sulfate proteoglycans (HSPGs) lead to the attachment of sporozoites to hepatocytes and trigger sig...

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Detalles Bibliográficos
Autores principales: Zhao, Jinghua, Bhanot, Purnima, Hu, Junjie, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999272/
https://www.ncbi.nlm.nih.gov/pubmed/27560376
http://dx.doi.org/10.1371/journal.pone.0161607