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A Comprehensive Analysis of Plasmodium Circumsporozoite Protein Binding to Hepatocytes
Circumsporozoite protein (CSP) is the dominant protein on the surface of Plasmodium sporozoites and plays a critical role in the invasion by sporozoites of hepatocytes. Contacts between CSP and heparin sulfate proteoglycans (HSPGs) lead to the attachment of sporozoites to hepatocytes and trigger sig...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999272/ https://www.ncbi.nlm.nih.gov/pubmed/27560376 http://dx.doi.org/10.1371/journal.pone.0161607 |