Cargando…

Archaerhodopsin Selectively and Reversibly Silences Synaptic Transmission through Altered pH

Tools that allow acute and selective silencing of synaptic transmission in vivo would be invaluable for understanding the synaptic basis of specific behaviors. Here, we show that presynaptic expression of the proton pump archaerhodopsin enables robust, selective, and reversible optogenetic synaptic...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Gaby, Mohamady, Zhang, Yu, Wolf, Konstantin, Schwiening, Christof J., Paulsen, Ole, Shipton, Olivia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999416/
https://www.ncbi.nlm.nih.gov/pubmed/27524609
http://dx.doi.org/10.1016/j.celrep.2016.07.057