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A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance

AMP-activated protein kinase (AMPK) in the ventromedial nucleus of the hypothalamus (VMH) and orexin (OX) in the lateral hypothalamic area (LHA) modulate brown adipose tissue (BAT) thermogenesis. However, whether these two molecular mechanisms act jointly or independently is unclear. Here, we show t...

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Detalles Bibliográficos
Autores principales: Martins, Luís, Seoane-Collazo, Patricia, Contreras, Cristina, González-García, Ismael, Martínez-Sánchez, Noelia, González, Francisco, Zalvide, Juan, Gallego, Rosalía, Diéguez, Carlos, Nogueiras, Rubén, Tena-Sempere, Manuel, López, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999418/
https://www.ncbi.nlm.nih.gov/pubmed/27524625
http://dx.doi.org/10.1016/j.celrep.2016.07.045