Cargando…

A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance

AMP-activated protein kinase (AMPK) in the ventromedial nucleus of the hypothalamus (VMH) and orexin (OX) in the lateral hypothalamic area (LHA) modulate brown adipose tissue (BAT) thermogenesis. However, whether these two molecular mechanisms act jointly or independently is unclear. Here, we show t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martins, Luís, Seoane-Collazo, Patricia, Contreras, Cristina, González-García, Ismael, Martínez-Sánchez, Noelia, González, Francisco, Zalvide, Juan, Gallego, Rosalía, Diéguez, Carlos, Nogueiras, Rubén, Tena-Sempere, Manuel, López, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999418/ https://www.ncbi.nlm.nih.gov/pubmed/27524625 http://dx.doi.org/10.1016/j.celrep.2016.07.045

Ejemplares similares

Central Ceramide-Induced Hypothalamic Lipotoxicity and ER Stress Regulate Energy Balance
por: Contreras, Cristina, et al.
Publicado: (2014)

Estradiol Regulates Brown Adipose Tissue Thermogenesis via Hypothalamic AMPK
por: Martínez de Morentin, Pablo B., et al.
Publicado: (2014)

Obesity induces resistance to central action of BMP8B through a mechanism involving the BBSome
por: Rial-Pensado, Eva, et al.
Publicado: (2022)

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
por: Martínez-Sánchez, Noelia, et al.
Publicado: (2017)

Genetic Targeting of GRP78 in the VMH Improves Obesity Independently of Food Intake
por: Liñares-Pose, Laura, et al.
Publicado: (2018)

κ-Opioid Signaling in the Lateral Hypothalamic Area Modulates Nicotine-Induced Negative Energy Balance
por: Seoane-Collazo, Patricia, et al.
Publicado: (2021)

Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress
por: González-García, Ismael, et al.
Publicado: (2018)

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
por: López, Miguel, et al.
Publicado: (2010)

mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol
por: González-García, Ismael, et al.
Publicado: (2018)

Hypothalamic mTOR Signaling Mediates the Orexigenic Action of Ghrelin
por: Martins, Luís, et al.
Publicado: (2012)

Lack of Ovarian Secretions Reverts the Anabolic Action of Olanzapine in Female Rats
por: Skrede, Silje, et al.
Publicado: (2017)

Glucagon Control on Food Intake and Energy Balance
por: Al-Massadi, Omar, et al.
Publicado: (2019)

BMP8 and activated brown adipose tissue in human newborns
por: Urisarri, Adela, et al.
Publicado: (2021)

Orexin, serotonin, and energy balance
por: Mavanji, Vijayakumar, et al.
Publicado: (2021)

Lack of Hypophagia in CB1 Null Mice is Associated to Decreased Hypothalamic POMC and CART Expression
por: Lage, Ricardo, et al.
Publicado: (2015)

Editorial: Hypocretins/Orexins
por: López, Miguel, et al.
Publicado: (2020)

Activity-Based Anorexia Induces Browning of Adipose Tissue Independent of Hypothalamic AMPK
por: Fraga, Angela, et al.
Publicado: (2021)

Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance
por: Quiñones, Mar, et al.
Publicado: (2015)

Hypothalamic KLF4 mediates leptin's effects on food intake via AgRP
por: Imbernon, Monica, et al.
Publicado: (2014)

The brain and brown fat
por: Contreras, Cristina, et al.
Publicado: (2015)

AMPK-Dependent Mechanisms but Not Hypothalamic Lipid Signaling Mediates GH-Secretory Responses to GHRH and Ghrelin
por: Vázquez, María J., et al.
Publicado: (2020)

Incendiary Leptin
por: Seoane-Collazo, Patricia, et al.
Publicado: (2020)

Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway
por: Contreras, Cristina, et al.
Publicado: (2017)

Olanzapine-Induced Hyperphagia and Weight Gain Associate with Orexigenic Hypothalamic Neuropeptide Signaling without Concomitant AMPK Phosphorylation
por: Fernø, Johan, et al.
Publicado: (2011)

O-GlcNAcylation: A Sweet Hub in the Regulation of Glucose Metabolism in Health and Disease
por: Gonzalez-Rellan, Maria J., et al.
Publicado: (2022)

Sequential Exposure to Obesogenic Factors in Females Rats: From Physiological Changes to Lipid Metabolism in Liver and Mesenteric Adipose Tissue
por: Novelle, Marta G., et al.
Publicado: (2017)

MECHANISMS IN ENDOCRINOLOGY: The gut–brain axis: regulating energy balance independent of food intake
por: Nogueiras, Ruben
Publicado: (2021)

Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala
por: Pineda, Rafael, et al.
Publicado: (2021)

Regulation of Chemerin and CMKLR1 Expression by Nutritional Status, Postnatal Development, and Gender
por: Sanchez-Rebordelo, Estrella, et al.
Publicado: (2018)

Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase
por: Martínez de Morentin, Pablo B., et al.
Publicado: (2012)

Functional Changes Induced by Orexin A and Adiponectin on the Sympathetic/Parasympathetic Balance
por: Messina, Antonietta, et al.
Publicado: (2018)

Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway
por: Romero-Picó, Amparo, et al.
Publicado: (2022)

Orexin A Enhances Pro-Opiomelanocortin Transcription Regulated by BMP-4 in Mouse Corticotrope AtT20 Cells
por: Fujisawa, Satoshi, et al.
Publicado: (2021)

SAT269 Orexin Activates Adrenocortical Steroidogenesis With Upregulation Of BMP Signaling By Human H295R Cells
por: Soejima, Yoshiaki, et al.
Publicado: (2023)

p53 and energy balance: meeting hypothalamic AgRP neurons
por: Al-Massadi, Omar, et al.
Publicado: (2018)

Hypothalamic AMPK and energy balance
por: López, Miguel
Publicado: (2018)

Functional cardiac orexin receptors: role of orexin-B/orexin 2 receptor in myocardial protection
por: Patel, Vanlata H., et al.
Publicado: (2018)

Hypothalamic kappa opioid receptor mediates both diet‐induced and melanin concentrating hormone–induced liver damage through inflammation and endoplasmic reticulum stress
por: Imbernon, Monica, et al.
Publicado: (2016)

Orexins in the clinical course of bipolar disorder
por: Moya-Lacasa, C., et al.
Publicado: (2021)

Thyroid hormones induce browning of white fat
por: Martínez-Sánchez, Noelia, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_sp3gb6ke7b4umt0cj92cl0db70