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Towards Profiles of Resistance Development and Toxicity for the Small Cationic Hexapeptide RWRWRW-NH(2)

RWRWRW-NH(2) (MP196) is an amphipathic hexapeptide that targets the bacterial cytoplasmic membrane and inhibits cellular respiration and cell wall synthesis. In previous studies it showed promising activity against Gram-positive bacteria and no significant cytotoxicity or hemolysis. MP196 is therefo...

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Detalles Bibliográficos
Autores principales: Wenzel, Michaela, Prochnow, Pascal, Mowbray, Catherine, Vuong, Cuong, Höxtermann, Stefan, Stepanek, Jennifer J., Albada, H. Bauke, Hall, Judith, Metzler-Nolte, Nils, Bandow, Julia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999427/
https://www.ncbi.nlm.nih.gov/pubmed/27617260
http://dx.doi.org/10.3389/fcell.2016.00086